11 results
diagnosis differential erythematosus hematology lupus management systemic anemia causes criteria cryoglobulinemia cryoglobulins eularacr glomerulonephritis hemolytic huv hypocomplementemic igg4 pathophysiology progressive
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... Pathophysiology #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Urticaria and hypocomplementemia ... against MPO • Complement ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology ... #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... • Low serum C4 complement ... erythematosus (SLE ... diagnosis #types #classification ... #rheumatology #
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Differential Diagnosis Algorithm ... Autoimmune • ITP • SLE ... HUS • DIC • Vasculitis ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Non-autoimmune rheumatologic ... RNP antibodies, Complement ... Erythematosus #Diagnosis #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... anticoagulant • Complement ... #EULARACR #Classification ... #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic ... Differential #Diagnosis #Rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... genotypes): SS, SC, SE ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... #workup #hematology
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
aortitis, mimics vasculitis ... - ↑ IgE, ↓ complement ... • Classification ... Diagnosis #Management #Rheumatology
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