29 results
diagnosis differential management rheumatology hematology nephrology cardiology lupus pulmonary renal testing aki classification druginduced endocarditis glomerular hypertension nephrotic secondary syndromes
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Membranoproliferative glomerulonephritis ... Post/pauci immune glomerulonephritis ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... , and SLE) • Urinalysis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... #Vasculitis #differential ... #diagnosis #algorithm
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
rapidly progressive glomerulonephritis ... ANCA Associated Vasculitis ... anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... - Normal Complement
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... osmolarity If cause ... and signs • Glomerulonephritis ... / Vasculits: ANCA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Skin ulcers - Glomerulonephritis ... Cryoglobulins Cause ... • Low serum C4 complement ... erythematosus (SLE
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... (Glomerulonephritis ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... Discontinuation of causal ... • Immunologic Workup ... 80% - Low complement
Causes of Approach to Altered Level of Consciousness - Workup Clinical Exam - Focal • Trauma •
Causes of Approach ... Consciousness - Workup ... Hemorrhage • See ... Refer to Blood Work ... #algorithm #Causes
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Autoimmune • ITP • SLE ... HUS • DIC • Vasculitis ... #Causes #Hematology
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