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differential rheumatology management lupus hematology nephrology testing druginduced erythematosus glomerular glomerulonephritis nephrotic systemic table acute aki aloc altered anemia bronchiectasis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... , and SLE) • Urinalysis ... #rheumatology #classification
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... • Immunologic Workup ... 80% - Low complement ... #rheumatology #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Autoimmune • ITP • SLE ... HUS • DIC • Vasculitis ... #Algorithm #Causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... • Low serum C4 complement ... #types #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Approach to Altered Level of Consciousness - Workup Clinical Exam - Focal • Trauma •
Causes of Approach ... Consciousness - Workup ... Hemorrhage • See ... #diagnosis #workup ... #algorithm #Causes
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... • Immunologic Workup ... Positive in 60-80% of cases ... 80% - Low complement ... Erythematosus #Diagnosis
Causes of Polyneuropathy - Differential Diagnosis Algorithm • Metabolic: DM, Hypothyroidism, CKD, Cirrhosis, Nutritional deficiency •
Causes of Polyneuropathy ... - Differential Diagnosis ... Paraneoplastic, CTD (SLE ... RA, Sjogren’s), Vasculitis ... #Algorithm #causes
Bronchiectasis: diagnosis and management Causes of localized -> diffuse bronchiectasis Foreign body, Bronchial stenosis (tumor, .. ),
Bronchiectasis: diagnosis ... management Causes ... RA, Sjögren, SLE ... #Differential #workup ... #algorithm #pulmonary
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... Diagnosis Baseline ... Glomerulonephritis / Vasculits ... #causes
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