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diagnosis rheumatology erythematosus causes criteria management vasculitis acidosis arthropathies arthropathy champs clinicopathology comparison cryoglobulinemia cryoglobulins disorders druginduced elevation eularacr hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... #Low #Complement ... Mnemonic #diagnosis #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... versus DIL • Laboratory ... 80% - Low complement ... #lupus #Systemic
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... ANA level above laboratory ... anticoagulant - Low complement ... #Rheumatology #SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... 90% - Low complement ... months to years) Systemic ... versus DIL • Laboratory ... 80% - Low complement
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... anticoagulant • Complement ... #Criteria #SLE ... #Systemic #Lupus
Lupus Classification Spontaneous Lupus - Cutaneous Lupus Erythematosus (CLE) - Systemic Lupus Erythematosus Drug-Induced Lupus - Drug-Induced
Lupus Classification ... ) - Systemic Lupus ... Drug-Induced Systemic ... #Classification ... rheumatology #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... and fever) and laboratory ... Skin Disease Classification ... permanent alopecia Differential ... #Systemic #Lupus
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... lupus erythematosus ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • Low serum C4 complement ... lupus erythematosus ... (SLE), rheumatoid ... diagnosis #types #classification
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