16 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... DrFlashHeart #Lupus #Nephritis ... #SLE #Classification ... #Classes #differential ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... ulcers, Lupus nephritis ... Positive in 60-80% of cases ... 80% - Low complement ... Usual therapeutic management
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... treat non-renal SLE ... therapy to treat class ... treat extra-renal SLE ... #management #nephrology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... 90% - Low complement ... ulcers, Lupus nephritis ... Positive in 60-80% of cases ... 80% - Low complement
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus Nephritis ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... , Class Ill or IV ... lupus nephritis ... anticoagulant • Complement ... #Criteria #SLE
Bronchiectasis: diagnosis and management 

Causes of localized -> diffuse bronchiectasis
Foreign body, Bronchial stenosis (tumor, .. ),
diagnosis and management ... Causes of localized ... RA, Sjögren, SLE ... Bronchiectasis #diagnosis #management ... Differential #workup #algorithm
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Exudative Effusion:
 - Pulmonary
     •
Causes of Pleural ... Differential Diagnosis Algorithm ... Inflammatory (RA, SLE ... Cirrhosis • Nephrotic ... #Causes #Pulmonary
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Nephrotic ... Differential #Diagnosis #Algorithm ... #causes