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diagnosis rheumatology differential acute agglutinin aki anemia causes cold cryoglobulinemia disease gammopathy hematology hemolytic hypocomplementemic injury kidney mgrs monoclonal nephrology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... #HUV #Pathophysiology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Infections: HCV ... infection, HBV ... infection, HIV infection ... • Low serum C4 complement ... diagnosis #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... Serologies for Cryoglobulins ... #rheumatology #classification
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... Glomerulonephritis / Vasculits ... immunoglobulins, cryoglobulins ... pressure • TTP / HUS ... #AKI #Workup #Algorithm
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Mycoplasma, EBV, HIV ... temperatures by fixing complement
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
guide subtype classification ... tubulopathy) - Complement ... glomerulopathy) - Cryoglobulin ... formation causing vasculitis
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