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diagnosis differential rheumatology causes nephrology renal acute acutekidneyinjury cryoglobulinemia cryoglobulins erythematosus gammopathy glomerulonephritis hsct hypertension igg4 injury kidney lupus management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Granulomatous disease ... against MPO • Complement ... #rheumatology #classification
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Kidney Injury - Classification ... - Small vessel vasculitis ... prolonged prerenal AKI ... EricsMedicalLectures/ #AKI ... Kidney #Injury #Classification
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Kidney Injury (AKI ... - Pre-renal disease ... — 21% - AKI ... Glomerulonephritis or vasculitis ... Nephrology #Diagnosis #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... receptor type 2) - ALKI ... neurofibromatosis, vasculitis ... , Gaucher disease ... Hypertension #PHTN #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... • Low serum C4 complement ... • IgA vasculitis ... • Vasculitis ... diagnosis #types #classification
HSCT related renal disease - AKI and CKD Acute Kidney Injury: Acute GvHD 2-4, Pre renal state,
related renal disease ... - AKI and CKD ... body irradiation, Complement ... #AKI #differential ... #diagnosis #algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Classification: ... ANCA-associated vasculitis ... • Mesenteric vasculitis ... RNP antibodies, Complement
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
IGG-4 RELATED DISEASE ... fibroinflammatory disease ... aortitis, mimics vasculitis ... - ↑ IgE, ↓ complement ... • Classification
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
refers to kidney disease ... end-stage kidney disease ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis
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