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diagnosis differential nephrology rheumatology workup acute classification injury kidney nephrotic renal acutekidneyinjury disease initial management membranoproliferative mpgn nephritic nephritis progressive
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... - Skin, glomeruli ... Urticaria and hypocomplementemia ... : - Kidneys: glomerular ... against MPO • Complement
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative Glomerulonephritis ... (MPGN) AKA: Mesangiocapillary ... dysmorphic RBC, RBC casts ... formation along glomerular ... Membranoproliferative #Glomerulonephritis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... #Vasculitis #differential ... #diagnosis #algorithm
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
- Small vessel vasculitis ... - TTP/HUS • Glomerular ... Post-infectious glomerulonephritis ... tubular necrosis (causes ... prolonged prerenal AKI
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
rhabdo/TLS) Causes ... related) - Glomerulonephritis ... or vasculitis — ... Nephrology #Diagnosis #Algorithm ... #Causes #Differential
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... #diagnosis #glomerulonephritis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Workup Algorithm ... osmolarity If cause ... and signs • Glomerulonephritis ... / Vasculits: ANCA ... #Workup #Algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
• Kidneys: Non-glomerular ... (Glomerulonephritis ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... diagnosis #initial #testing
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... renal failure (glomerulonephritis ... EGPA) • Renal: (AKI ... Goodpasture's cause ... hypercellular glomeruli
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