Hypocomplementemia complement vasculitis algorithm testing classification anemia workup disease

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10 results

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Hemolytic Anemia ... Differential Diagnosis Algorithm ... cardiac valve, vasculitis ... #workup #hematology ... #testing

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Granulomatous disease ... against MPO • Complement ... #rheumatology #classification

Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

Pancytopenia - Workup ... Differential Diagnosis Algorithm ... Eating disorders ... Acquired Aplastic Anemia ... Metastatic Disease

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Cryoglobulins (Vasculitic ... • Symptoms of anemia ... • hemolytic anemia ... Positive Coombs testing ... temperatures by fixing complement

Pancytopenia - Workup ... Differential Diagnosis Algorithm ... Eating disorders ... Acquired Aplastic Anemia ... Metastatic Disease

Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

Differential Diagnosis Algorithm ... hematology for workup ... hemolysis, deficiency anemia ... Rheumatologic, Vasculitides ... , IBD, Celiac disease

Recommended initial testing for patients being evaluated for glomerular disease

24-hour urine collection - Quantify proteinuria.

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

anti-Smith Ab, low complements ... Classification: ... ANCA-associated vasculitis ... lymphopenia, low PLT • Anemia ... RNP antibodies, Complement

Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.

Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins

refers to kidney disease ... Diagnostic Workup ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis

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