9 results
A System for Vasculitides 

#Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... #Small #Medium ... Large #Vessel #Size ... #Classification ... #Differential #Algorithm
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... Pathogenesis and Clinical ... infiltrate the tissue site ... Activation of complement ... - Cutaneous small
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
abnormalities SMALL ... Schonlein Purpura (IgA ... Findings by Vessel Size ... against MPO • Complement ... #rheumatology #classification
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
involvement of small ... vessels (medium-sized ... : SLE +++ • IgA ... vasculitis (10% ... lesions #diagnosis #clinical
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Low serum C4 complement ... • IgA vasculitis ... • Cutaneous small-vessel ... diagnosis #types #classification
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
specific) COMMON CLINICAL ... aortitis, mimics vasculitis ... Essential Criteria: Clinical ... , ↓ complement ... • Classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... anti-Smith Ab, low complements ... Skin Disease Classification ... inflammation of the small ... RNP antibodies, Complement
Causes of Small Bowel Ulceration
The diagnosis of IBD can’t be made or excluded by biopsies alone
Causes of Small ... this requires clinical ... depends on the site ... causes in the small ... Vascular: Ischaemia, Vasculitis
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Clinical Clues: ... Immunofixation (SIFE ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis