8 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Rapidly Progressive ... staining): • Low ... Complement: Post-strep ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
alveolar hemorrhage + rapidly ... progressive glomerulonephritis ... anti-GBM) 10%: - Low ... Complement Levels ... Vasculitis - Normal Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
, proteinuria, rapidly ... progressing GN ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Low levels mixed
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, proteinuria, Rapidly ... progressing GN ... Pauci immune GN (rapidly ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... system (node) with progression ... B-Cell ~90% • Low ... correlated with rapid ... #differential #algorithm
Esophageal Dysphagia - History and Diagnosis Algorithm
Solids only - Probably Structural
 - Intermittent, Non-Progressive: Ring and/or
and Diagnosis Algorithm ... Intermittent, Non-Progressive ... and/or web - Progressive ... • Slow +/- ... Stricture • Rapid
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
proteinuria with rapid ... Pathogenesis: How ... Damages Kidneys • Low ... tubulopathy) - Complement ... function and prevent progression