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differential nephrology causes hematology workup adrenal endocrinology hyponatremia sodium disease hypokalemia insufficiency management rheumatology vasculitis acth amenorrhea cardiology criticalcare deficiency
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... : - Kidneys: glomerular ... against MPO • Complement ... (Low levels mixed
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... #Deficiency #Testing ... #Algorithm #hematology ... #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... in monitoring low-level ... or alternative complement ... #testing #workup ... #diagnosis #glomerulonephritis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... Algorithm Persistent ... present on repeat testing ... including overnight testing ... • Drugs Glomerular
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... in monitoring low-level ... or alternative complement ... #workup #diagnosis ... #initial #testing
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... Idiopathic • Normal Complement ... #differential #diagnosis ... #algorithm #rheumatology
Syphilis Serologic Testing - Treponemal and Non-Treponemal Testing Algorithms Treponemal Testing: • Confirmatory or Screening - Detection
Syphilis Serologic Testing ... Non-Treponemal Testing ... Algorithms Treponemal ... Definitive • Low ... #diagnosis #Treponemal
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
Algorithm INDICATIONS ... FOR TESTING: • ... Cortisol, Saliva • Low ... Cushing #Syndrome #diagnosis ... #algorithm #endocrinology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup and Diagnosis ... Algorithm • Confirm ... mimics, repeat testing ... • Evidence of glomerular ... #Algorithm #Workup
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