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differential criticalcare rheumatology treatment hematology cardiology foamed lupus diarrhea disease druginduced glomerular nephrology nephrotic pancytopenia sle stratification acute anesthesia anesthesiology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... #Deficiency #Testing ... #Algorithm #hematology ... #diagnosis
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
Hyperthyroidism (low ... Algorithm Radioactive ... workup choices ... AND management options ... #Algorithm #Workup
Diarrhea Workup and Management Algorithm in Transplant Patients First Tier Microbiologic-Testing: 1. C. difficile PCR (Stool) 2. CMV qPCR
Diarrhea Workup ... and Management Algorithm ... #Diarrhea #Workup ... #Management #Algorithm ... #Transplant #diagnosis
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
PET-CT Imaging (→ Diagnostic ... rheumatoid factor), ± hypocomplementemia ... Related #Disease #diagnosis ... #management #phenotypes ... #workup #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... • Immunologic Workup ... 60-80% - Low ... complement - 50 ... Erythematosus #Diagnosis
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Algorithm Consumption ... Production - Flow ... Eating disorders
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Algorithm Consumption ... Production - Flow ... Eating disorders
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... in >90% - Low ... complement - Rare ... #rheumatology #diagnosis ... #management
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