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differential hematology rheumatology vasculitis bleeding bruising champs classification deficiency fe fever glomerulonephritis hemolysis hemorrhage hypocalcemia immunecompromised immunocompromised intravascular iron low
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential Diagnosis ... Algorithm Extravascular ... perfringens - Complement-Mediated ... #Algorithm #Causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement
Causes of Hypocalcemia - Differential Diagnosis Algorithm • Extravascular: Pancreatitis, surgery, acute phosphate intake and renal
Causes of Hypocalcemia ... - Differential Diagnosis ... Algorithm • Extravascular ... #Differential #Diagnosis ... #Algorithm #Causes
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... • Disseminated Intravascular ... #Algorithm #Causes
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... - Differential Diagnosis ... Algorithm • Blood ... • Iron loss: Intravascular ... #Causes #Fe #algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... - Differential Diagnosis ... Algorithm Blood ... #Differential #Diagnosis ... #Algorithm #Causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... RTA, TYPE I RTA Diagnosis ... #Rheumatology #Diagnosis
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