13 results
diagnosis differential rheumatology vasculitis fuo hematology causes classification infectiousdiseases management unknown acute agglutinin anemia blood champs chronic coccidioidomycosis cold cryoglobulinemia
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... Urticarial #Vasculitis #HUV
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... A - Atypical HUS ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Vasculitis: • Fevers ... against MPO • Complement ... (Low levels mixed
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
of Unknown Origin ... Differential Diagnosis Algorithm ... PE Bacterial - Organ ... Infection: • HIV ... Differential #Diagnosis #Algorithm
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
anti-GBM) 10%: - Low ... Complement Levels ... Vasculitis - Normal Complement ... other hemorrhagic fevers ... , atypical HUS,
Causes of Acute Onset Fever - Differential Diagnosis Algorithm Viral: • Rhinovirus • Influenza Virus • Parainfluenza
of Acute Onset Fever ... Differential Diagnosis Algorithm ... Coronavirus • HIV ... Septic Shock Acute Organ ... Differential #Diagnosis #Algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis: • Fevers ... and branches • Fever ... HTN • Check: HBV ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
injury and end-organ ... Cryoglobulins Cause Organ ... infection, HBV ... factor level • Low ... serum C4 complement
Possible Algorithm for Workup of Fever of Unknown Origin (FUO) Tier 1 Workup: • CBC, comprehensive metabolic
Possible Algorithm ... for Workup of Fever ... of Unknown Origin ... blood cultures • HIV ... #Fever #Unknown
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
originate from a low-grade ... Mycoplasma, EBV, HIV ... temperatures by fixing complement ... Symptoms: High fevers
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