23 results
diagnosis differential management rheumatology causes hematology vasculitis risk stratification antibiotics classification ebm erythematosus evaluation febrile idsa infant lp lupus neutropenia
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Vasculitis: • Fevers ... against MPO • Complement ... (Low levels mixed
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
anti-GBM) 10%: - Low ... Complement Levels ... Vasculitis - Normal Complement ... other hemorrhagic fevers
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis: • Fevers ... and branches • Fever ... Coronary arteries • Fever ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Constitutional domain: Fever ... anticoagulant • Complement ... proteins domain: Low ... C3 or low C4, Low ... C3 and low C4
IDSA Algorithm for the Initial Management of Fever and Neutropenia LOW RISK • Antidpated neutropenia < 7
IDSA Algorithm for ... Management of Fever ... Neutropenia LOW ... #neutropenic #fever ... #IDSA #Algorithm
Systolic Murmurs - Differential Diagnosis Algorithm Benign / Flow / Hyperdynamic: • Pregnancy • Fever • Anemia Supravalvular
Differential Diagnosis Algorithm ... Benign / Flow ... Pregnancy • Fever ... • Rheumatic Fever ... Differential #Diagnosis #Algorithm
“Step by Step” – the new kid on the block – aims to risk stratify this
components of the algorithm ... be considered “low ... an infant with fever ... Infant #StepByStep #Algorithm ... Stratification #Fever
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