13 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... Urticarial #Vasculitis #HUV ... Pathophysiology #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... A - Atypical HUS ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... #differential #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Coronary arteries - Fever ... Vasculitis: • Fevers ... against MPO • Complement
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Differential Diagnosis Algorithm ... perfringens - Complement-Mediated ... anemia • Acute ... MAHA (TTP, DIC, HUS ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... DIC, TTP, HELLP, HUS ... bartonella (oroya fever ... #workup #hematology ... #testing
Algorithm for the Evaluation of Acute Diarrhea (< 7 days)
Are the following present?
   1.
Algorithm for the ... Evaluation of Acute ... Ova and parasite testing ... HIV infection or ... Bloody diarrhea, fever
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Fevers ... and branches • Fever ... HTN • Check: HBV ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Chest Pain Diagnosis and Management Algorithm
STEMI:
 - Hx: Pressure like CP, Radiation to arm/jaw, CAD risk
and Management Algorithm ... onset, severe, tearing ... friction rub, Fever ... caustic ingestion, HIV ... Pneumothorax: - Hx: Acute
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Positive Coombs testing ... Mycoplasma, EBV, HIV ... temperatures by fixing complement ... Symptoms: High fevers ... hemolytic #anemia #hematology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
children with acute ... rash observed in acute ... multiforme • Acute ... include: infections (HSV ... differential #diagnosis #dermatology