13 results
diagnosis rheumatology hematology renal classification pathophysiology pulmonary syndromes agglutinin anemia causes champs clinicopathology cold disease disorders erythematosus gammopathy glomerulonephritis headache
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... Formation -> Vasculitis ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... Mnemonic #diagnosis #differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive ... staining): • Low ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
proteinuria, rapidly progressing ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Syndromes and Mimics - Differential ... hemorrhage + rapidly progressive ... anti-GBM) 10%: - Low ... Complement Levels ... - Normal Complement
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic ... #Differential #
Causes of Headache - Differential Diagnosis Algorithm Primary: Tension, Migraine, Cluster Extracranial: Medications, Sinusitis, TMJ disorder, Cervicogenic, Glaucoma,
of Headache - Differential ... Diagnosis Algorithm ... Aneurysm, Hemorrhage, Vasculitis ... Pseudotumor Cerebri, Low ... Diagnosis #Causes #algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Diagnosis Algorithm ... system (node) with progression ... B-Cell ~90% • Low ... #algorithm
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... non-specific, ESR usually low ... hematuria, RBC casts, low ... Path: rapidly progressive
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... permanent alopecia Differential ... , lymphopenia, low ... RNP antibodies, Complement
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