13 results
rheumatology differential management huv igg4 renal urticarial workup champs classification ddxof disease gammopathy glomerulonephritis hematology im low mgrs mimic mnemonic
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV) Diagnosis of HUV 1) Chronic urticaria 2) Leukocytoclastic vasculitis 3)
Diagnosis and Management ... of Hypocomplementemic ... (HUV) Diagnosis ... 3) Hypocomplementemia ... TerrierBen #Hypocomplementemic
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... Formation -> Vasculitis ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
- Differential Diagnosis ... hemorrhage + rapidly progressive ... anti-GBM) 10%: - Low Complement ... - Normal Complement ... #Differential #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... proteinuria, rapidly progressing ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement
Vasculitis Mimics #Diagnosis #IM #Rheum #Vasculitis #Workup #Mimic #Mimics #Differential #Algorithm #Ddxof
Vasculitis Mimics ... #Diagnosis #IM ... #Rheum #Vasculitis ... #Workup #Mimic ... #Algorithm #Ddxof
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive ... staining): • Low Complement ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... proteinuria, Rapidly progressing ... Differential Diagnosis ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
PET-CT Imaging (→ Diagnostic ... rheumatoid factor), ± hypocomplementemia ... No necrosis, No vasculitis ... glucocorticoids - reconsider diagnosis ... Related #Disease #diagnosis
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
inflammation -> progressive ... vasculitis • ... breast, skin DIAGNOSIS ... - ↑ IgE, ↓ complement ... #IGG-4 #IGG4 #Diagnosis
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