11 results
diagnosis differential rheumatology aki nephrology acute injury management workup acutekidneyinjury champs classification disease gammopathy glomerulonephritis hematology huv igg4 low mgrs
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... Formation -> Vasculitis ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Kidneys -> glomerulonephritis ... against MPO • Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... • Limited to Kidney ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... musculoskeletal systems • Kidneys ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
lesions, meninges, kidneys ... rheumatoid factor), ± hypocomplementemia ... No necrosis, No vasculitis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Emboli, Thrombosis, Vasculitis ... #AKI #Acute #Kidney ... Diagnosis #nephrology #causes ... #algorithm
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... osmolarity If cause ... Glomerulonephritis / Vasculits ... #AKI #Workup #Algorithm
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Guide to Acute Kidney ... rhabdo/TLS) Causes ... Glomerulonephritis or vasculitis ... Nephrology #Diagnosis #Algorithm ... #Causes #Differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... Xerostomia • Dental caries ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis
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