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diagnosis management differential hematology rheumatology champs disorders erythematosus gammopathy granulomatosis hodgkins hypercalcemia lupus lymphoma lymphoproliferative malignancy mgrs mnemonic monoclonal nonhodgkin
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... B-Cell ~90% • Low ... Responsive to Treatment ... Lymphoproliferative #Disorders #Classification ... #differential #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... #rheumatology #classification
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... Blood Count - Low ... may be high or low ... Treatment • Early ... #diagnosis #classification
Orofacial Granulomatosis - Diagnosis and Management Algorithm Idiopathic OFG: isolated swelling of the lips, BX+ non-caseating granuloma Melkersson-Rosenthal
and Management Algorithm ... Mycotic ulcer, Lymphoma ... or develop CD Low ... Resolve w Rx of IBD Algorithm ... #treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... • Non-Hodgkins lymphoma ... • B cell lymphoma ... • MALT Lymphoma ... Adenocarcinoma Treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Skin Disease Classification ... , lymphopenia, low ... RNP antibodies, Complement
Treatment algorithm for malignancy-associated hypercalcemia • Aggressive IV hydration • IV Bisphosphonate +/- Calcitonin • Renal
Treatment algorithm ... : Dalysis with low ... Loop diuretic • Lymphoma ... hypercalcemia #treatment ... #management #algorithm
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
smoldering myeloma/lymphoma ... guide subtype classification ... Damages Kidneys • Low ... tubulopathy) - Complement ... microangiopathy Treatment
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