2101 results
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV)

Diagnosis of HUV
1) Chronic urticaria 
2) Leukocytoclastic vasculitis 
3)
Management of Hypocomplementemic ... vasculitis 3) Hypocomplementemia ... TerrierBen #Hypocomplementemic
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... of Hypocomplementemic ... TerrierBen #Hypocomplementemic ... Vasculitis #HUV #Pathophysiology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
cardiac output) - Low ... SvO2 → Low PaO2 ... COHb, MetHb) - Low ... CaO2 → Low SvO2 ... diagnosis #causes #pathophysiology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Insufficiency - Pathophysiology ... aldosterone will be low ... Low ACTH leads to ... stimulation, thus low ... Insufficiency #Pathophysiology
Cardiac Cycle - Pathophysiology
 - Atrial Contraction
 - Isovolumetric Contraction
 - Rapid Ventricular Ejection
 - Slow
Cardiac Cycle - Pathophysiology ... Ventricular Ejection - Slow ... Ventricular Filling - Slow ... Cardiac #Cycle #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... -> Uric Acid (low ... Urate Nephropathy (low ... Syndrome #TLS #Pathophysiology
Coronary Oxygen Balance 

Myocardial Oxygen Demand <-> Coronary Artery Blood Flow <-> Oxygen Availability

#cardiac #oxygen #pathophysiology
Coronary Artery Blood Flow ... cardiac #oxygen #pathophysiology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
NH4+ (relatively low ... ammonia #hepatology #pathophysiology
Hypothermia in Sepsis - Pathophysiology
 • 20% of septic pts → HYPOTHERMIA
 • Increased mortality 62%
Hypothermia in Sepsis - Pathophysiology ... hypothermia in sepsis: Low ... Hypothermia #sepsis #pathophysiology