11 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Binding #KBinders #Kayexelate ... #Comparison #Table ... Pharmacology #Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... disturbances (including hypokalemia ... Potassium #Binding #Hyperkalemia
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... minutes) • Stool - Kayexylate ... LouLectures #Hyperkalemia ... management #potassium #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Elimination (see Table ... emcrit.org/ibcc/hyperkalemia ... management of hyperkalemia ... #Hyperkalemia
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #pharmacology #table ... #comparison #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
• LDH ↑ • Hyperkalemia ... /Late - Hypercalcemia ... per day until stable ... Dialysis for severe hyperkalemia ... causes #treatment #nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Inexpensive - Treats hypocalcemia ... Lower risk of hypercalcemia ... edgarvlermamd - Nephrology ... Phosphate #Binders #Table ... #Pharmacology #Nephrology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyporeflexia: • Hypercalcemia ... Hyperreflexia: • Hypocalcemia ... differential #diagnosis #table ... #neurology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Present (Uosm ≥100): Hypovolemia ... , Hypervolemia with ... differential #diagnosis #table ... #sodium #nephrology
Landau's Reaction (Reflex)  on Physical Exam

Landau's reaction is investigated holding the baby firmly under the
child will be able ... Reaction #Reflex #PhysicalExam ... clinical #video #Neurology ... #Peds #Pediatrics