19 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
(e.g. ... Metolazone) 5) Potassium-sparing ... diuretics (e.g. ... #pharmacology # ... nephrology #medications
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
(e.g. mannitol) ... (e.g. furosemide ... 4) Thiazides (e.g ... HCTZ) 5) Potassium-sparing ... Pathophysiology #Nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
, Mechanism of Action ... , Effects, Clinical ... #Medications #Pharmacology ... #summary #table ... #nephrology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Sites of Action ... Diuretics 1) ... ) Loop agents (eg ... #Sites #Action ... #nephrology #pharmacology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... for Management ... treatment #pharmacology ... #table #comparison ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
and Management ... heparinized tube) • ECG ... Elimination (see Table ... #Treatment #potassium ... #nephrology #K
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... in the later (e.g ... which are short acting ... ) to normalize Potassium ... Early nephrologv
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... the Nonspecific Cation ... nocturnal enuresis • Prevention ... #Nephrology #Pharmacology ... #Medications #Table
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department
 • Place on cardiac
algorithm for management ... of acute hyperkalemia ... monitor 12-lead ECG ... #treatment #potassium ... #high #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
tubule (DCT) Clinical ... with thiazide diuretic ... (renal potassium ... Syndrome #diagnosis #nephrology ... #management #pathophysiology