10 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... #Binding #Hyperkalemia ... #medications #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Metabolic acidosis - Hyperkalemia ... cantaloupe #hyperkalemia
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Metabolic acidosis - Hyperkalemia ... images/12834 #hyperkalemia
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
intracellular calcium causes ... - Hyperkalemia ( ... Because digoxin binds ... , in states of hypokalemia ... (or low potassium
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... emcrit.org/ibcc/hyperkalemia ... management of hyperkalemia ... #Hyperkalemia ... #nephrology #K
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
• LDH ↑ • Hyperkalemia ... Hyperuricemia • Hyponatremia ... Monitor potassium ... Dialysis for severe hyperkalemia ... #treatment #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine Na+K ... Present (Uosm ≥100): Hypovolemia ... , Hypervolemia with ... differential #diagnosis #table ... #sodium #nephrology
Pragmatic diagnostic algorithm for hypokalemia. 
***Typical presentations: 
 • Vomiting: urine Na/Cl > 1.6, low urine
algorithm for hypokalemia ... urine Na/Cl > 1.6, low ... Tubulopathy: urine K/ ... genetic testing *If hypokalemia ... reporting.137,138 #hypokalemia
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
130 mEq/L • Potassium ... trial • Minimal K ... Is Dangerous in Hyperkalemia ... • Saline May Cause ... NS #comparison #pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Hypercalcemia ... Kidney stones caused ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table