8 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
sparing diuretics ... lysis syndrome - Rhabdomyolysis ... Medications 2. ... #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
sparing diuretics ... lysis syndrome - Rhabdomyolysis ... Medications 2. ... #potassium #high ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine Na+K ... can be high or ... Present (Uosm ≥100): Hypovolemia ... differential #diagnosis #table ... #sodium #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, K-sparing diuretics ... only if no clear cause ... Elimination (see Table ... Treatments: • K-Binding ... #nephrology #K
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
works by directly binding ... intracellular calcium causes ... high potassium levels ... (or low potassium ... Pathophysiology #cardiology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
; High-Ceiling Diuretics ... Kidney stones caused ... and euvolemic hyponatremia ... #Nephrology #Pharmacology ... #Medications #Table
Pragmatic diagnostic algorithm for hypokalemia. 
***Typical presentations: 
 • Vomiting: urine Na/Cl > 1.6, low urine
urine Na/Cl > 1.6, low ... urine Na/Cl < 0.7, high ... Tubulopathy: urine K/ ... correcting serum potassium ... Other medications