11 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... sparing diuretics ... Medications 2. ... #potassium #high ... #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
urinary losses: • High ... Alkalosis: Emesis, Diuretics ... diagnosis #Algorithm #differential ... #potassium #nephrology ... #low
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... sparing diuretics ... Medications 2. ... #potassium #high ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine Na+K ... can be high or ... #differential # ... diagnosis #table ... #sodium #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, K-sparing diuretics ... only if no clear cause ... Elimination (see Table ... Treatments: • K-Binding ... #nephrology #K
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
works by directly binding ... intracellular calcium causes ... high potassium levels ... (or low potassium ... Pathophysiology #cardiology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
; High-Ceiling Diuretics ... Kidney stones caused ... and euvolemic hyponatremia ... #Nephrology #Pharmacology ... #Medications #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Differential Diagnosis ... Hyperuricemia • Hyponatremia ... Monitor potassium ... Loop diuretics for ... #treatment #nephrology
Pragmatic diagnostic algorithm for hypokalemia. 
***Typical presentations: 
 • Vomiting: urine Na/Cl > 1.6, low urine
urine Na/Cl > 1.6, low ... urine Na/Cl < 0.7, high ... Tubulopathy: urine K/ ... Other medications ... #algorithm #nephrology