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Management and Complications of Cirrhosis and Ascites

Ascites Workup Algorithm
Ascites Management
Refractory Ascites
Hyponatremia
Spontaneous Bacterial Peritonitis (SBP)
Hepatic Hydrothorax
AKI in
Management and Complications ... Ascites Workup ... Ascites Hyponatremia ... #gastroenterology ... #hepatology
Ascites - Differential Diagnosis and Workup Algorithm

•
Perform paracentesis:
 • Cell count and diff 
 • Total
Ascites - Differential ... Diagnosis and Workup ... #Differential # ... Diagnosis #Algorithm #gastroenterology ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Idiosyncratic #differential ... #gastroenterology ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... develops (DIC, ascites ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #pathophysiology
Ascites - Diagnosis and Management Summary
Paracentesis studies: cell count + differential, albumin, protein, culture
 • Serum-ascites-albumin-gradient
and Management ... : cell count + differential ... this may lead to reduced ... #Diagnosis #Management ... #Summary #Hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... (at injection sites ... ♀, ↑Age, ESRD Pathophysiology ... #HIT #Heparin #Induced ... #Treatment #Hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... bile ducts Differential ... Sarcoidosis, Drug-induced ... cholangitis #diagnosis #workup ... #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
, V and II • Reduced ... protein C and S Pathophysiology ... or venipuncture sites ... causes #treatment #management ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... endothelial damage • Induce ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... Based on number of sites ... classification #hematology ... #oncology #management