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diagnosis treatment syndrome tb tuberculosis activetb hepatology signs abscess aflp apml comparison differential differentiation disease extraarticular fatty hepatopulmonary leukostasis liver
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... affecting the lungs ... and Culture • CXR ... disease • Check CXR ... TB #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... affecting the lungs ... and Culture • CXR ... disease • Check CXR ... TB #Diagnosis #Management
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Abscess Pathophysiology ... Blood cultures • CXR ... early disease) • CXR ... #Abscess #pulmonary ... #differential #causes
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases ... of active pulmonary ... decreased reflexes Pathophysiology ... tissue damage - CXR ... for concomitant pulmonary
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... , dyspnea, +/- CXR ... TLS #diagnosis #management ... #hematology
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
pleural effusion on CXR ... inflammation tends to cause ... disease/pulmonary ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... granulomas within the lungs ... are not caused ... e.g. incidental CXR
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... AP, ↑INR, ↑BUN/Cr ... #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... common • Imaging: CXR ... - pulmonary opacities ... Diagnosis: >3 symptoms ... #hematology #oncology
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