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management hematology oncology apml cauda differentiation encephalopathy equina leukostasis lysis myelitis posterior pres reversible sweet tls transverse tumor
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... - ACS, AKI, acute ... WBC >100k, + lab signs ... #TLS #diagnosis
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine • MCC- acute ... axial T1 and T2 Treatment ... decompression #CaudaEquina ... diagnosis #causes ... #neurology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... : >3 symptoms, or ... initiation • Differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... : Acute onset 2 ... Reversible course Differential ... #neurology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... Episcleritis Signs ... Causes: - Idiopathic ... Treatment: - Systemic ... #diagnosis #dermatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... or without back pain ... • Bilateral signs ... and/or symptoms ... #differential
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