14 results
Carbamazepine Toxicity

Carbamazepine (CBZ) is an antiepileptic drug commonly prescribed for seizure disorders, trigeminal neuralgia, neuropathic pain,
Carbamazepine Toxicity ... Carbamazepine (CBZ ... neuralgia, neuropathic pain ... #Toxicology #Diagnosis ... SideEffects #Adverse #Pharmacology
Parkinson's Plus Syndromes - Atypical Parkinsonism
Main motor symptoms:
 • Tremors
 • Limb rigidity
 • Bradykinesia
Other symptoms
Parkinsonism Main ... Corticobasal syndrome (CBS ... (DLB) • Drug-induced ... #Parkinsonism #diagnosis
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced ... Pleuritic chest pain ... pneumonitis Diagnosis ... of amiodarone-induced ... #Amiodarone #Induced
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Signs: weight gain ... un lymphatic Diagnostic ... endomyocardial biopsy Pharmacology ... #heartfailure #diagnosis ... management #cardiology #pharmacology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Pain, Agitation, ... glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic ... #CriticalCare #diagnosis
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
brain • Weight Gain ... irreversible • Drug induced ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
Severe low back pain ... Differential Diagnosis ... extremity reflexes - reduced ... Laboratory studies: • CBC ... #differential #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... • Hydralazine-Induced ... , testes -> pain ... Lab Tests: • CBC ... polyarteritis, drug-induced
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Checkpoint Inhibitor Toxicity ... Main Toxicities ... CheckpointInhibitor #Toxicity ... SideEffects #Table #Diagnosis ... #Pharmacology #
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
malaise) - Muscle pain ... Inflammation and pain ... - Drug induced ... - CBC may also ... Sweet #Syndrome #diagnosis