12 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... Pulmonary arterial ... receptor type II-like ... Hypertension #PHTN #Classification ... #Diagnosis #Differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... Autoimmune diseases • Clinical ... translocation • Types: Classification ... involvement Differential ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... organ dysfuxtion, ICU ... APML #diagnosis #management ... #hematology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... progressing GN • New pulmonary ... glomerulonephritis) • Anti-GBM ... #diagnosis #rheumatology ... #classification
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Growers (Runyon Classification ... grp I-III): Pulmonary ... Growers (Runyon Classification ... Disease: Clinical ... NTM #Infections #differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Hodgkin Lymphoma - Clinical ... -95% of cases) Classification ... Immunohistochemical studies (to differentiate ... #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
VII, X, V and II ... organ damage Clinical ... variants of both • Acral ... causes #treatment #management ... #hematology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... cardiomyopathy • Pulmonary ... Clinical • Under-recognized ... Avoid ARBs • ICD ... support for patients clinically