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diagnosis management differential cardiology hepatology neurology rheumatology table activetb algorithm comparison disease hepatopulmonary latenttb lung lysis obstetrics oncology pocus pregnancy
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... 5 or elevated Cr ... - pulmonary opacities ... organ dysfuxtion, ICU ... diagnosis #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... organ damage • Treatment ... acid, Elevated Cr ... Low calcium • Treatment ... diagnosis #management #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment Stop offending agents: • List as allergies
Symptoms (DRESS) Syndrome ... Treatment Stop ... LFTs daily • Cr ... #Treatment #Management ... #dermatology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Pathogenesis and clinical ... osteoporosis -> Incr ... , sleep apnea, cor ... pulmonale #PraderWilli
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
of Pregnancy (ICP ... weeks • Typical clinical ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... differential #diagnosis #icp
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... of the above Treatment ... of Clinical TLS ... monitoring • Consider ICU ... #Tumor #Lysis #Syndrome
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... Clinical Picture ... Diagnosis - Clinical ... Clinical DX: - ... Bedside: ice pack
Figure 3 HRCT-LUS correlation in normal lung, pulmonary congestion, rheumatoid lung disease, idiopathic pulmonary fibrosis. Notes: (A)
in normal lung, pulmonary ... due to alveolar syndrome ... B-lines in one IC ... fibrotic alveolar syndrome ... #Clinical #Diagnosis
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Unknown cause Treatment ... of emergency, ICU ... #summary #rheumatology
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