16 results
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
antivirals (DAAs) for chronic ... (HCV) infection ... Antivirals #table #treatment ... #hcv #medications ... infectiousdisease #hepatology
Hepatitis B Phases and Treatment
Phase 1 - HBeAg+ Chronic Infection
Phase 2 - HBeAg+ Chronic Hepatitis
Phase 3
and Treatment ... Infection Phase ... Infection Phase ... HepBV #Phases #Treatment ... Management #diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Coagulation Failure Infections ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... non-essential drug/HDS treatments ... Hepatocellular: Viral infections ... hepatitis fibrosis ... Diagnosis #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... Parenchyma • Infectious ... Toxic: Alcohol, Medication ... , TPN • Infectious ... Acute #algorithm #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... 10-20x normal - Infection ... 5-10x normal - Chronic ... Patterns #Liver #Injury ... #hepatology #LFTs
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... HBV infections ... Chronic Hepatitis ... Diagnosis #Management #Treatment ... #Hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... • Reaction to Medications ... : Chronic infections ... Diagnosis #Algorithm #hematology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Indications Treatment ... • HIV/HCV co-infection ... with severe liver injury ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Diagnosis: • Infections ... : Hepatitis A/B/ ... , HSV, VZV • Medications ... Differential #Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis