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rheumatology differential erythematosus signs systemic druginduced management arthropathies arthropathy autoantibodies autoimmune comparison complications ddxof dermatology dil disorders joint maculopapular mimickers
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... inflammation on skin ... #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... constitutional symptoms ... #table #rheumatology ... #diagnosis #management
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Algorithm Pathophysiology ... sulfa-drug - Skin ... #Dermatology #Rash ... Maculopapular #Scaling #Color
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... 69% - Malar rash ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Disease Classification ... Differential Diagnosis ... : • Symptoms limited
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms ... NPSLE rare, Malar rash ... is rare in DIL, SCLE-DIL ... #DIL #rheumatology ... #diagnosis #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... such as systemic lupus ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... classification
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... : • Gottron rash ... pancreas, stomach, colon ... pancreas, stomach, colon ... Extramuscular manifestations
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