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differential vasculitis dermatology sle erythematosus management signs systemic adult causes complications cryoglobulinemia cryoglobulins disease disorders glomerulonephritis joint lymphomas lymphoproliferative manifestations
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Disease Classification ... Differential Diagnosis ... : • Symptoms limited ... #Rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation on skin ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... such as systemic lupus ... Presentation - Systemic Symptoms ... #rheumatology # ... classification
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... (lupus, RA, Sjogren's ... cryoglobulins • Skin ... #Algorithm #Causes
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... , breast CA - Hematologic ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... Labs/Diagnosis: ... (e.g. systemic lupus ... #types #classification ... #rheumatology #
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
with urticarial rash ... the chest/trunk Symptoms ... maculopapular skin ... Stills #disease #AOSD ... #diagnosis #rheumatology
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