17 results
hematology disease hemophagocytic hlh lymphohistiocytosis syndrome checklist oncology stills activation adult adultonset anemia anesthesia anesthesiology anterior aplastic apml calcium cardiac
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Life-threatening ... synovitis (40%) Treatment ... #rheumatology # ... diagnosis #management ... #treatment
LVOTO due to SAM on POCUS Echocardiogram Septic patient after IV fluids and initiation of Levophed. Worsening
Echocardiogram ... Diagnosis? ... Management? ... #ultrasound #Cardiology ... #PLAX #clinical
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 Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Treatment - Mild ... • If uncontrolled ... Stills #disease #AOSD ... #diagnosis #rheumatology ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE], AOSD ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Symptomatic anemia Diagnosis ... megaloblastic anemia Treatment ... neutropenic fever ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... • Bicytopenia Treatment ... If no response HLH ... #management #treatment ... #hematology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
thoracotomy is a better treatment ... tamponade recurs. ❿ Plan ... definitive management ... specialist referral. ⓫ Plan ... #Management #Workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... high risk if WBC ... Subacute-Acute: • Common: fever ... Renal Failure Treatment ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... : - If febrile ... Syndrome #TLS #diagnosis ... #management #hematology
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