11 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... hepatitis • Pulmonary ... Prunelle Getten #AdultOnset ... #management #treatment ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... Differentiation #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
, difficult to diagnose ... Life-threatening ... BrighamChiefs #AdultOnset ... Disease #AOSD #rheumatology ... #diagnosis #management
Endocarditis checklist
Initial evaluation
 • Peripheral blood cultures (three sets at three different sites)
 • Additional culture
Endocarditis checklist ... endocarditis w/ septic pulmonary ... • Persistent fever ... #criticalcare #diagnosis ... #management
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
ANA) [especially if ... search ANA and aPL ... 9) Unexplained fever ... including in children (pediatric ... erythematosus #rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
symptoms • Rheumatologic ... Increased protein level ... normal glucose level ... device removal (if ... #Management #Infections
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
Pause surgery if ... reservoir bag and APL ... adult, 10 ml.kg-1 paediatric ... Intraoperative #Checklist ... #Diagnosis #Management
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
Pause surgery if ... reservoir bag and APL ... o Aspiration, pulmonary ... Intraoperative #Checklist ... #Diagnosis #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
decrease in HIV-1 RNA level ... Lymphadenitis, pulmonary ... leukoencephalopathy (PML ... continued • If ... #Management
Intraoperative Hypoxia / Desaturation / Cyanosis - Guidelines for Crises in Anaesthesia
Using these steps from start
reservoir bag and APL ... o Aspiration, pulmonary ... Intraoperative #Checklist ... #Diagnosis #Workup ... #Management #Workup