13 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Life-threatening ... #AdultOnset #Stills ... Disease #AOSD #rheumatology ... #diagnosis #management
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... • If uncontrolled ... #Adult #onset #Stills ... #rheumatology # ... management
Endocarditis checklist
Initial evaluation
 • Peripheral blood cultures (three sets at three different sites)
 • Additional culture
Endocarditis checklist ... endocarditis w/ septic pulmonary ... • Persistent fever ... #criticalcare #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... +, Adult-onset Still ... #management #treatment ... #summary #rheumatology
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... active ROM +/- fever ... , chills, malaise ... 90% sensitive in pediatrics ... anal Cxs) • *** If
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management ... 38 degrees • Chills ... decubitus - air fluid level ... pneumonectomy if ... Lung #Abscess #pulmonary
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Prophylaxis: • Attempt if ... high risk if WBC ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... #management #hematology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Generalized: • Chills ... night sweats, fever ... Cerebral > Splenic, pulmonary ... Differential Diagnosis ... #management #cardiology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Lymphadenitis, pulmonary ... lymphadenitis, pulmonary ... Fever, chills, lack ... continued • If ... #Management