19 results
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) - Diagnosis ... and Management ... Criteria - Fever ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... dL) - Heparin if ... #diagnosis #causes ... #treatment #management ... #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... neutropenic fever ... Aplastic #Anemia #diagnosis ... #management #treatment ... #hematology
THROMBOELASTOGRAPHY (TEG)
General Principle
• A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
problems with coagulation ... Thromboelastography #Diagnosis ... #Management #CriticalCare ... #Hematology #Interpretation
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
, difficult to diagnose ... malignant) to diagnose ... Life-threatening ... Disease #AOSD #rheumatology ... #diagnosis #management
Normal Thromboelastogram - Specific parameters represent the 3 phases of the cell-based model of haemostasis: initiation,
amplitude of 2mm); i.e ... achieve a certain level ... clot formation; i.e ... lysis time (s) #Diagnosis ... #Hematology #Coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Prolonged PT and aPTT If ... • Reduced liver ... #differential #hematology ... #coagulation
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... • Clinical: fever ... , ↓ Fibrinogen level ... #management #treatment ... #summary #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... intravascular coagulation ... #Differential #Diagnosis ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... lymph node, or liver ... If no response HLH ... #management #treatment ... #hematology