20 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... Nephrotic Syndromes ... hematuria. ... #Diseases #Nephritic ... #Nephrotic #Syndromes
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... Differential Diagnosis Renal ... : - Glomerular ... membrane, Alport syndrome ... - Interstitial nephritis
Causes of Hematuria - Glomerular vs Non-glomerular

== Glomerular ==
- Glomerulonephritis 
- Thin basement membrane disease 

==
Causes of Hematuria ... basement membrane disease ... == Kidney - ... Pyelonephritis - Renal ... #Differential #Urology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
basement membrane disease ... syndrome: • ... disease Renal ... Causes of Hematuria ... #urology #nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... • Evidence of glomerular ... for renal biopsy ... if cause not identified ... by UW IM Residency
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Immunofluorescence Microscopy (IM ... Microscopy (EM) Haematuria ... /nephritis • Lupus ... Nephrotic syndrome ... #diseases #nephrology
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
suggest intrinsic renal ... disease - Timing ... Diagnosis #EM #IM ... #Urology #Hematuria ... Differential #Algorithm #Ddxof
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... osmolarity If cause ... Interstitial nephritis ... #causes
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... a.k.a. cardiorenal syndrome ... - TTP/HUS • Glomerular ... tubular necrosis (causes ... Acute interstitial nephritis
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... broad - Advanced kidney ... disease Red blood ... , renal tuberculosis ... syndrome ("Maltese