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diagnosis nephrology differential algorithm renal microscopy nephritic syndrome urology acute aki blood casts classification comparison diseases glomerulonephritis injury proteinuria testing
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
/nephritic syndromes ... the patient have glomerular ... casts or dysmorphic ... RBCs in urine)? ... #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... #Diseases #Nephritic
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... • Evidence of glomerular ... if cause not identified ... by UW IM Residency ... Diagnosis #Algorithm #Workup
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
basement membrane disease ... syndrome: • ... disease Renal ... Causes of Hematuria ... #urology #nephrology
Causes of Hematuria - Differential Diagnosis Renal: - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... Diagnosis Renal: - Glomerular ... membrane, Alport syndrome ... - Interstitial nephritis ... Medullary sponge kidney
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Immunofluorescence Microscopy (IM ... Microscopy (EM) Haematuria ... /nephritis • Lupus ... Nephrotic syndrome ... #diseases #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... arbitrarily defined as urine ... urine sediment ... Hematuria may be ... #syndrome #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... osmolarity If cause ... • Interstitial nephritis ... #causes
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... a.k.a. cardiorenal syndrome ... - TTP/HUS • Glomerular ... tubular necrosis (causes ... Acute interstitial nephritis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... and concentrated urine ... broad - Advanced kidney ... disease Red blood ... syndrome ("Maltese
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