18 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... can mimic common infections ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
) Treatment Primary ... associated with infection ... autoimmune disease, treatment ... #Treatment #management ... #hematology
Kerion
Raised, boggy lesion with heaped up purulent nodules 
Caused by host's response to a fungal ringworm
purulent nodules Caused ... fungal ringworm infection ... mentagrophytes) Clinical ... Lymphadenopathy Treatment ... #Diagnosis #Management
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Management ... are caused by members ... HIV/AIDS, CGD) Clinical ... presentations: • Pulmonary ... #treatment #fungal
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... hyperinflammatory syndrome caused ... Triggers: ▪ Infections ... Clinical Presentation ... #Hematology #HemeOnc
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Lung Abscess - Clinical ... Lung #Abscess #pulmonary ... #management #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... transplantation CLINICAL ... and cauda equina TREATMENT ... Hospital of Baltimore IM ... Syndrome #diagnosis #management