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sle disease druginduced erythematosus syndrome systemic capillary cardiology cerebritis clarksons cns comparison dil infectiousdiseases leak legionnaires leishmaniasis leptospira leptospirosis neurology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Positive in 60-80% of cases ... life-threatening • Treatment ... Erythematosus #Diagnosis ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Leptospirosis Pathogen: Leptospira (interrogans, kirschneri, noguchii) Risk Factors: • Occupational exposure - Farmers, ranchers, trappers, veterinarians • Recreational
non-productive cough, nausea ... failure • Severe pulmonary ... Leptospirosis #Leptospira #microbiology ... #diagnosis #treatment ... #management
Visceral Leishmaniasis - Diagnosis and Management Summary Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi Where: South Asia, East
and Management ... Weight Loss • Can cause ... 20 mg/kg/d IV/IM ... #management #treatment ... infectiousdiseases #microbiology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... filling +++ (risk of pulmonary ... leak #syndrome #diagnosis ... #management #timeline ... #treatment #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
constitutional symptoms • Treatment ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment ... #management
Legionnaires' Disease Clinical features: • Gl- nausea, vomiting, diarrhea • Hyponatremia • Elevated transaminases • CRP >100
respond to B-Lactams Treatment ... Extra-pulmonary: ... Hospital of Baltimore IM ... Legionnaires #Disease #diagnosis ... #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... , INC risk PE, Pulmonary ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Acute Recurrent Pericarditis = recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
symptoms, >1/4 of AP cases ... Systemic symptoms: pulmonary ... #Pericarditis #diagnosis ... #management #treatment ... #rheumatology #
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