5 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... (HLH) Treatment ... associated with infection ... EricsMedicalLectures/ #HLH #Hemophagocytic ... #management #hematology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... filling +++ (risk of pulmonary ... of infections) ... syndrome #diagnosis #management ... #rheumatology
Legionnaires' Disease
Clinical features:
 • Gl- nausea, vomiting, diarrhea
 • Hyponatremia
 • Elevated transaminases
 • CRP >100
respond to B-Lactams Treatment ... Other Legionella Infections ... Extra-pulmonary: ... Hospital of Baltimore IM ... Disease #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Hemophagocytic Lymphohistiocytosis ... hyperinflammatory syndrome caused ... Triggers: ▪ Infections ... #HLH #Hemophagocytic ... #Hematology #HemeOnc