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management druginduced lupus rheumatology causes classification erythematosus nephrology pharmacology systemic table acidosis aki blood dermatology elevation encephalopathy hematuria high hyperkalemia
Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a
Injury • Drug ... 24-72 hours of drug ... • Treatment includes ... #pharmacology #toxicology ... #diagnosis #management
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
Prostate cancer • Medications ... Goodpasture's syndrome, SLE ... Renal #Transplant #differential ... #diagnosis #kidney ... urine #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... myalgia, serositis, Kidney ... life-threatening • Treatment ... #comparison #table ... #rheumatology #diagnosis
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
SLE High risk ... for 1 year of treatment ... Erythematosus #medications ... #risk #differential ... #diagnosis #rheumatology
Drug-Induced Hypertension - Common Medications Corticosteroids (prednisone) Sympathomimetics (amphetamine, pseudoephedrine) SNRl's (duloxetine, venlafaxine) Calcineurin Inhibitors (tacrolimus, cyclosporine)
Drug-Induced Hypertension ... 6 most common drug ... classes that I see ... #Differential # ... Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... extremities Drug ... Kidney biopsy if ... Thrombosis highest risk ... activation and/or medications
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Diagnosis Eosinophilic ... the mainstay of treatment ... patients with kidney ... immunocompromised host Drug ... #Diagnosis #comparison
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
renin-angiotensin-aldosterone axis; T risk ... erythematosus (SLE ... Tubulointerstitial diseases: SLE ... #Hyperkalemia #Differential ... #Diagnosis #High
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Risk factors 3. ... Reversible course Differential ... Electrolyte abnormality, Medication ... /Drug toxicity, ... epilepticus Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... again we might see ... circulation If drugs ... before beginning treatment ... - HIV/HAART medications
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