10 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Management of Idiosyncratic ... acetaminophen/APAP) • Idiosyncratic ... Liver #Injury #Idiosyncratic
Drug-Induced Liver Injury - Pathophysiology
Indirect
Idiosyncratic
Direct

BWH Medicine Chiefs @BrighamChiefs

#DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Pathophysiology Indirect Idiosyncratic
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
Pre renal AKI Idiosyncratic
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
replacing the BM - Idiosyncratic ... deficiency-rare Adult: - Idiosyncratic
Propofol Frenzy on Neurological Examination

Propofol frenzy; Presented with a cluster of seizures, now on Propofol, being
stop Propofol [idiosyncratic
Neuroleptic Malignant Syndrome - Diagnosis
Neuroleptic Malignant Syndrome is an idiosyncratic reaction to antipsychotic medications classically characterized
Syndrome is an idiosyncratic
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
Unconventional or idiosyncratic
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Sarcoidosis Idiosyncratic
Chloramphenicol - Antibiotics Class Overview

– 50S ribosomal inhibitor.   IV or PO (but PO form
anemia – rare, idiosyncratic
Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
 • Sympathomimetic -
Neuroleptic Malignant - Ideosyncratic