741 results
Causes of Urticaria

Immunoglobulin E (IgE) mediated

 - Aeroallergens

 - Contact allergen

 - Food allergens

 - Insect
Immunoglobulin E (IgE ... infections Non-IgE ... Differential #Urticaria #IgE
Asthma: immunopathogenesis. 
Allergens attach to, and are taken up by, dendritic cells that he the respiratory
and release IgE ... allergens bridge two IgE
Assessment and Treatment of Severe Asthma, According to Inflammatory Phenotypes, in Patients without a Response to
omalizumab includes an IgE
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV)

Diagnosis of HUV
1) Chronic urticaria 
2) Leukocytoclastic vasculitis 
3)
Rituximab, anti-IgE
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Drug Reactions IgE-mediated ... pruritic than lgE-mediated
Allergic Bronchopulmonary Aspergillosis (ABPA)
WHAT IS IT?
Hypersensitivity response to Aspergillus fumigatus in the airways
 • Primarily affects
Elevated Total IgE ... Aspergillus specific lgE ... and Aspergillus IgG ... voriconazole) • Anti-lgE
Alpha-gal Syndrome (AGS) - Diagnosis Algorithm
Does patient have recurrent episodes of urticaria, angioedema or isolated GI
for alpha-gal IgE
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
eosinophil counts and IgE
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
autoimmune): - Hyper IgE
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
IgM MGUS: • Serum ... IgM monoclonal ... myeloma Non-IgM ... or IgG isotype ... (rarely IgD or IgE