41 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Megakaryopoiesis • Aplastic Anemia ... Quinidine • HIT ... #Differential #
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Heparin-Induced Thrombocytopenia ... • "4 T's" clinical ... score: - Thrombocytopenia ... Heparin #Induced #Thrombocytopenia ... #HIT #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Sideroblastic anemia ... Thrombotic idiopathic thrombocytopenia ... key #diagnosis #differential ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Risks factor for HIV ... changes), high MCV anemia ... Platelet #Disorders #Differential ... Causes #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... Thrombocytosis #Differential ... Algorithm #Causes #Hematology
Cotton Wool Spots

Caused by microinfarcts. Exploded ganglion cell axons extrude their axoplasm into retina. Long DDx:
hypertension, diabetes, HIV ... , severe anemia ... or thrombocytopenia ... ophthalmology #Clinical
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... etc) - Viral: HIV ... #Differential # ... Diagnosis #Framework #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... - Hemolytic anemia ... Ig A vasculitis/HSP ... #nonpalpable #dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Schistocytes, thrombocytopenia ... ARUPLabs #Hemolytic #Anemia ... #Differential #
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced Thrombocytopenia ... consumption → thrombocytopenia ... Diagnosis: • Clinical ... non-heparin A/C if clinical ... Management #Treatment #Hematology