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diagnosis differential vasculitis classification lupus systemic amebiasis autoantibodies cdc parasite pathophysiology sle acanthamoeba ana antinuclear aortitis balamuthia champs complement cryoglobulinemia
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
P - Post/pauci immune ... Systemic Lupus Erythematosus ... #differential #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... mimickers, Other auto-immune ... Systemic #Lupus #Erythematosus ... #differential #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Systemic Lupus Erythematosus ... (ACLE) • Erythematous ... Non-autoimmune rheumatologic ... context of primary immune ... #Diagnosis #Rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
syndrome - Immune-complex-induced ... systemic lupus erythematosus ... Vessels #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Systemic lupus erythematosus ... Erdheim-Chester), Immune ... Differential #Diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
can activate the immune ... the deposit of immune ... Immune-Mediated ... systemic lupus erythematosus ... classification #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
inflammation • Pauci-immune ... purpuric macules • Erythematous ... • Ulcerated, erythematous ... rash #diagnosis #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
association with auto-immune ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology
Amebiasis - Balamuthia mandrillaris Life Cycle 1) Cysts 2) Trophozoite 3) Mitosis 4) Amebae (cysts and trophozoites) can enter humans
individuals who are immune ... with compromised immune ... #mandrillaris #LifeCycle ... pathophysiology #infectiousdiseases
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Necrotizing, pauci-immune ... respiratory tracts Immune ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... differential #diagnosis #rheumatology
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